Chief Information Security Officer

Company shown to members 🔒 · Remote · US only

US only12+ years required$260K/yrPublished 28 October 2026Looks fresh

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First recorded by Psst: 29 October 2026. Your first 3 jobs are free to apply to (the first right away, 2 more with your email). After that, the company and the apply link are for Psst members, from $4.99 for 7 days.

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The 20-second read

Experience
12+ years required
Where you can live
US only
Skills and tools
customer success, saas, compliance, hipaa, escalations
Job type
Full-time

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Job details

Where you can work
United States
Employment type
Full-time
Advertised pay
$260K/yr
Experience
12+ years required
Employer publication date
28 October 2026
First recorded by Psst
29 October 2026
Last checked at the source
10 November 2026

About the job

Transform healthcare with us.

At the company the company, we're redefining what's possible with Generative AI in healthcare. Our infrastructure provides the guardrails for safe AI governance, healthcare-specific agent creation, and real-time algorithm monitoring, working alongside leading the company systems to drive real change.

This is more than just a job. It's an opportunity to build the future of AI in healthcare, solve complex challenges, and make a lasting impact on patient care. If you're ambitious, innovative, and ready to move fast, we'd love to have you on board.

Job Summary

As the company the company scales its AI platform across leading the company systems and pharmaceutical sponsors, security is fundamental to protecting sensitive data, earning customer trust, and deploying AI responsibly in healthcare. As our Chief Information Security Officer (CISO), you will own our enterprise security strategy, risk posture, and security and privacy program end to end.

You will partner with executive leadership, Engineering, Product, Legal, and Commercial to embed security and data privacy into our products, infrastructure, AI workflows, and business operations. You will lead our approach to security governance, healthcare compliance, incident response, and enterprise customer trust while building the capabilities needed to support our continued growth.

This is an executive leadership role that combines strategic ownership with technical depth. You can translate complex security risks into clear business decisions, work directly with engineering teams on critical technical challenges, and build a rigorous security program without creating unnecessary friction for the business.

KEY RESPONSIBILITIES

Security Strategy & Executive Leadership

  • Own the company the company’s enterprise security strategy, risk posture, and roadmap, aligning priorities and investments with business objectives and the evolving threat landscape.
  • Advise executive leadership on material risks, risk acceptance decisions, security investments, and the implications of new products and customer engagements.
  • Establish security governance, policies, metrics, and accountability across the organization.
  • Build out and scale the security organization, determining the right mix of internal expertise, external partners, and essential capabilities as the company grows.

Product, Cloud & AI Security

  • Set technical security direction across application security, cloud infrastructure, identity and access management, vulnerability management, and secure software development.
  • Partner with Engineering and Product to embed security into architecture, development, testing, deployment, and production operations.
  • Establish safeguards for AI-enabled products and workflows, including protection of PHI across LLM integrations, AI agents, data pipelines, and connected systems.
  • Work directly with engineering leaders to resolve high-impact technical risks while balancing security rigor with product velocity.
  • Provide strategic direction and technical leadership in the design and implementation of a secure AI infrastructure, aligning architecture, governance, and risk controls with organizational security objectives and compliance requirements.
  • Oversee DevOps and cloud infrastructure during our current growth phase, ensuring reliable, scalable, and secure platform operations.

Healthcare Compliance & Enterprise Trust

  • Own the security program supporting HITRUST, SOC 2, and applicable customer and regulatory requirements, including control design, audit readiness, and ongoing effectiveness.
  • Partner with Legal, Privacy, Engineering, and business leaders to translate contractual and regulatory obligations into practical controls.
  • Serve as the senior security counterpart to the company system and pharmaceutical customers, leading security diligence, technical assessments, and escalations.
  • Partner with Commercial and Customer Success to resolve security-related deal blockers and build confidence in the company the company's security posture.
  • Evaluate third-party and vendor risks, and determine when additional frameworks or certifications, such as HITRUST, are warranted.

Incident Response & Operational Resilience

  • Own the security incident response program, including detection, escalation, investigation, containment, recovery, and post-incident remediation.
  • Establish and test incident response, business continuity, and disaster recovery plans, coordinating with executive leadership, Legal, customers, and external specialists when needed.
  • Support the Privacy Team in meeting HIPAA and state privacy law reporting obligations with robust risk assessments, incident response, and audit readiness processes.
  • Build the operating model, tools, processes, and external partnerships needed to maintain effective security operations as the company scales.
  • Drive security awareness and clear security ownership across Engineering, IT, and other business functions.

Required Qualifications

  • 12+ years of experience in information security or cybersecurity, including significant leadership experience at enterprise or high-growth technology companies.
  • Experience operating at CISO, VP of Security, or equivalent senior leadership level, with accountability for enterprise security strategy, risk management, and executive engagement.
  • Track record of building and scaling security programs, including foundational controls, governance, technical capabilities, and teams.
  • Deep technical understanding of cloud security, application security, identity and access management, vulnerability management, and incident response.
  • Experience owning or leading HIPAA and SOC 2 program success, including control implementation, audit readiness, and remediation.
  • Experience protecting sensitive or regulated data and translating compliance requirements into effective technical controls.
  • Experience leading enterprise customer security reviews and communicating security posture and risk to senior stakeholders.
  • Ability to influence executive leadership and cross-functional teams while balancing risk management with business priorities.

Desirable Qualifications

  • Experience at a high-growth healthcare technology, healthcare AI, life sciences technology, or enterprise SaaS company.
  • Experience securing AI-enabled applications, LLM-based systems, AI agents, or platforms handling sensitive healthcare data.
  • Experience with HITRUST, NIST Cybersecurity Framework, or NIST AI Risk Management Framework.
  • Experience presenting security posture, material risks, and investment recommendations to a board or board-level committee.
  • Hands-on experience leading or working closely with DevOps, SRE, or platform engineering teams.
  • Relevant certifications such as CISSP, CISM, or CCSP.

Why Join the company the company?

This is an opportunity to join a fast-growing company and a world-class team that is poised to change the healthcare industry. We are a passionate, mission-driven team building a category-defining product. We are backed by premier investors and are looking for founding team members who are excited to do the best work of their careers.

Our employees are integral to achieving our goals, so we are proud to offer competitive salaries with equity packages, robust medical/dental/vision insurance, flexible working hours, hybrid work options, and an inclusive environment that fosters creativity and innovation.

Our Commitment to Diversity

The company the company is an equal opportunity employer. We believe that a diverse and inclusive workplace is essential to our success, and we are committed to building a team that reflects the world we live in. We encourage applications from all the company individuals, regardless of race, color, religion, gender, sexual orientation, gender identity or expression, age, national origin, marital status, disability, or veteran status.

Pay & Benefits

The pay range for this role is between $260,000 and $330,000, and will depend on your skills, qualifications, experience, and location. This role is also eligible for equity and benefits.

Join our mission to revolutionize healthcare with AI. To apply, please send your resume through the application below.

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